研究员-凯发网

吴颉，研究员，博士生导师。2007年7月中国科学院过程工程研究所获得生物化工专业工学博士学位，毕业后留所工作至今。研究聚焦于新型生物医药制剂研究及应用。主持国家重大新药创制专项课题、国家重点研发计划课题、国家自然科学基金重点项目、面上项目（3项）及青年基金项目、北京市自然科学基金面上项目、中国科学院重点部署项目（课题主持）、中国科学院科技服务网络项目（课题主持）等。已在国内外期刊发表论文60余篇，包括nature materials, advanced materials, biomaterials, advanced healthcare materials等，两篇文章获elsevier集团颁发原创研究引用奖，获发明专利授权17项（欧洲、日本发明专利各1项）。获中国化工学会基础研究成果一等奖、中国颗粒学会自然科学一等奖、中国颗粒学会青年颗粒学奖等，现担任中国生物工程学会生物基材料专业委员会秘书长。

1.yongjuan zou#, xiaoxuan liu#, qiuting chen, hiroyuki oku, guanghui ma, jie wu*. acid-responsive immune-enhancing chitosan formulation capable of transforming from particle stabilization to polymer chain stabilization. acs applied materials & interfaces, 15, 11403-11415, 2023.

2.nan wu#, qiuting chen#, yongjuan zou, chunyu miao, guanghui ma, jie wu*. chitosan particle-emulsion complex adjuvants: the effect of particle distribution on the immune intensity and response type. carbohydrate polymers, 309, 120673, 2023.

3.yongjuan zou, nan wu, chunyu miao, hua yue, jie wu*, guanghui ma. a novel multiple emulsion enhanced immunity via its biomimetic delivery approach. journal of materials chemistry b, 8, 7365-7374, 2020.

4.yiqun du#, yufei xia#, yongjuan zou, yuning hu, jiaqi fu, jie wu*, xiao-dong gao*, guanghui ma*. exploiting the lymph-node-amplifying effect for potent systemic and gastrointestinal immune responses via polymer/lipid nanoparticles. acs nano, 13(12), 13809-13817, 2019.

5.yufei xia#, jie wu#, wei wei, yiqun du, tao wan, xiaowei ma, wenqi an, aiying guo, chunyu miao, hua yue, shuoguo li, xuetao cao, zhiguo su*, guanghui ma*. exploiting the pliability and lateral mobility of pickering emulsion for enhanced vaccination. nature materials, 17(2), 187-194, 2018.

6.yufei xia#, jie wu#, yiqun du, chunyu miao, zhiguo su*, guanghui ma*. bridging systemic immunity with gastrointestinal immune responses via oil-in-polymer capsules. advanced materials, 30(31), 1801067, 2018. 

7.fangfang nan#, jie wu#, feng qi, qingze fan, guanghui ma*, to ngai*. preparation of uniform-sized colloidosomes based on chitosan-coated alginate particles and its application for oral insulin delivery. journal of materials chemistry b, 2(42), 7403-7409, 2014.

8.feng qi#, jie wu#, guanqing sun, fangfang nan, to ngai*, guanghui ma*. systematic studies of pickering emulsions stabilized by uniform-sized plga particles: preparation and stabilization mechanism. journal of materials chemistry b, 2(43), 7605-7611, 2014.

9.yue-qi wang#, jie wu#, qing-ze fan, meng zhou, zhan-guo yue, guang-hui ma*, zhi-guo su. novel vaccine delivery system induces robust humoral and cellular immune responses based on multiple mechanisms. advanced healthcare materials, 3(5), 670-681, 2014.

10.youbin wu, wei wei, meng zhou, yueqi wang, jie wu*, guanghui ma*, zhiguo su. thermal-sensitive hydrogel as adjuvant-free vaccine delivery system for h5n1 intranasal immunization. biomaterials, 33(7), 2351-2360, 2012.